[Remote] VP, Global In Vitro - Scientific Operations
Note: The job is a remote job and is open to candidates in USA. Crown Bioscience is a leader in the field of drug discovery, specializing in oncology and immunology. The Global VP of In Vitro Scientific Operations will oversee global operations, ensuring high-quality data delivery and operational excellence while driving scientific innovation and capability development across multiple sites.
Responsibilities
- Lead all global in vitro scientific operations across Crown’s sites
- Ensure consistent and high-quality execution of in vitro studies, maintaining strong scientific rigor, reproducibility, and translational relevance
- Drive operational efficiencies through standardized workflows, SOP harmonization, and continuous improvement initiatives
- Oversee end-to-end operational workflows, including study design support, resource planning, execution, QC, reporting, and on-time delivery
- Drive improvements in productivity, reproducibility, cycle time, and cross-site alignment
- Establish and track operational KPIs (quality, timeliness, resource utilization, client satisfaction)
- Identify opportunities to expand and modernize in vitro capabilities
- Lead implementation of new technologies, automation, and translational assays supporting MoA, PK/PD linkage, and IND-enabling studies
- Partner with biomarker, in vivo, and translational science leaders to ensure integration across platforms
- Act as a senior scientific representative for key client meetings, supporting proposal development, study design, troubleshooting, and data interpretation
- Support BD strategy with strong scientific storytelling, customer retention insights, and expansion of strategic partnerships
- Guide teams in translating client program objectives into actionable in vitro study plans
- Ensure alignment between scientific operations, project management, quality, and commercial teams
- Support cross-site initiatives, including platform harmonization and global capability mapping
- Build a high-performance culture emphasizing scientific rigor, innovation, accountability, and client-centricity
- Provide strategic mentorship, succession planning, and competency development across assay platforms
- Oversee global in vitro budgets, headcount planning, capital equipment strategy, and site capacity allocations
- Support revenue planning, operational forecasting, and margin optimization
- Partner with finance and senior leadership to drive operational efficiency and scalability
Skills
- Ph.D. in cancer biology, immunology, pharmacology, molecular/cell biology, or related discipline
- 10+ years of experience in oncology/immunology preclinical research with deep expertise in in vitro assay platforms
- 7+ years of leadership experience managing scientific teams, ideally across multiple global sites
- Demonstrated track record in CRO scientific operations, with strong understanding of client expectations and data delivery requirements
- Extensive experience designing, executing, and interpreting mechanistic in vitro assays, immune effector studies, co-culture systems, and imaging-based platforms
- Proven ability to manage operational workflows, introduce new capabilities, and ensure high-quality scientific output
- Excellent communication skills, with experience in client-facing scientific roles
- Experience leading multi-site or global scientific operations within a CRO or service-based company
- Expertise with advanced or emerging in vitro technologies
- Deep understanding of oncology, immuno-oncology, and translational biology
- Strong program or portfolio management exposure within scientific operations
- Strong commercial partnership history with BD teams and biotech/pharma clients
- Cross-cultural leadership experience and ability to manage teams across time zones
Company Overview
- CrownBio is helping provide clarity of action in the fight against cancer and diabetes. It was founded in 2006, and is headquartered in Santa Clara, California, USA, with a workforce of 1001-5000 employees. Its website is http://www.crownbio.com.
Company H1B Sponsorship
- Crown Bioscience has a track record of offering H1B sponsorships, with 3 in 2025, 2 in 2024, 2 in 2023, 2 in 2021, 1 in 2020. Please note that this does not guarantee sponsorship for this specific role.
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